Cheapest one-way flights from Prague to Madrid in December from 52€

Best time to book flights for Prague (PRG) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Prague (PRG) to Madrid (MAD) in December 2025 (see full year).

One-Way flights

03 Dec Ryanair direct
04 Dec Ryanair direct
02 Dec Ryanair direct
09 Dec Ryanair direct
11 Dec Ryanair direct
19 Dec Ryanair direct
18 Dec Ryanair direct
21 Dec Ryanair direct
17 Dec Ryanair direct
22 Dec Iberia direct

Also check the deals for return flights from Prague to Madrid in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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