Cheapest one-way flights from Prague to Rome in September from 47€

Best time to book flights for Prague (PRG) to Rome (CIA) flights at AirHint

AirHint found the following cheapest one-way flights from Prague (PRG) to Rome (CIA) in September 2025 (see full year).

One-Way flights

11 Sep Ryanair direct
16 Sep Ryanair direct
06 Sep Ryanair direct
05 Sep Ryanair direct

Also check the deals for return flights from Prague to Rome in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rome

Cheap car rent in Rome