Cheapest one-way flights from Chicago to Santo Domingo in September from 114€

AirHint found the following cheapest one-way flights from Chicago (ORD) to Santo Domingo (SDQ) in September 2025 (see full year).

One-Way flights

30 Sep Spirit Airlines
06 Sep Spirit Airlines
15 Sep Spirit Airlines
08 Sep Spirit Airlines
16 Sep Spirit Airlines
03 Sep Spirit Airlines
07 Sep Spirit Airlines
02 Sep Spirit Airlines
05 Sep Spirit Airlines

Also check the deals for return flights from Chicago to Santo Domingo in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santo Domingo

Cheap car rent in Santo Domingo

Feel free to contact us with any feedback or request another flight research.