Cheapest one-way flights from Chicago to Panama City in September from 157€

AirHint found the following cheapest one-way flights from Chicago (ORD) to Panama City (PTY) in September 2025 (see full year).

One-Way flights

08 Sep Spirit Airlines
06 Sep Spirit Airlines
19 Sep Spirit Airlines
05 Sep Spirit Airlines
08 Sep Copa direct
06 Sep Copa direct
19 Sep Copa direct
05 Sep Copa direct

Also check the deals for return flights from Chicago to Panama City in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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