Cheapest one-way flights from Chicago to Prague in December from 249€

AirHint found the following cheapest one-way flights from Chicago (ORD) to Prague (PRG) in December 2025 (see full year).

One-Way flights

15 Dec Frontier Airlines
13 Dec Spirit Airlines
02 Dec Spirit Airlines
12 Dec TAP

Also check the deals for return flights from Chicago to Prague in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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