AirHint found the following cheapest one-way flights from Chicago (ORD) to Madrid (MAD) in December 2025 (see full year).
One-Way flights
| 31 Dec | Icelandair | ||
| 10 Dec | Icelandair | ||
| 05 Dec | TAP | ||
| 04 Dec | Spirit Airlines | ||
| 02 Dec | Icelandair | ||
| 07 Dec | Icelandair | ||
| 12 Dec | Frontier Airlines | ||
| 01 Dec | Spirit Airlines | ||
| 07 Dec | Iberia | direct | |
| 08 Dec | Iberia | direct |
Also check the deals for return flights from Chicago to Madrid in December.
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