Cheapest one-way flights from Chicago to Istanbul in September from 207€

AirHint found the following cheapest one-way flights from Chicago (ORD) to Istanbul (IST) in September 2025 (see full year).

One-Way flights

30 Sep Spirit Airlines
20 Sep Frontier Airlines
24 Sep Frontier Airlines
22 Sep Frontier Airlines
15 Sep TAP
23 Sep Spirit Airlines
19 Sep Frontier Airlines
17 Sep Spirit Airlines
16 Sep Spirit Airlines
22 Sep Turkish Airlines direct

Also check the deals for return flights from Chicago to Istanbul in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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