Cheapest one-way flights from Chicago to Istanbul in October from 181€

AirHint found the following cheapest one-way flights from Chicago (ORD) to Istanbul (IST) in October 2025 (see full year).

One-Way flights

07 Oct Spirit Airlines
04 Oct Spirit Airlines
19 Oct Spirit Airlines
01 Oct Spirit Airlines
15 Oct Frontier Airlines
02 Oct Spirit Airlines
29 Oct TAP
03 Oct Spirit Airlines
30 Oct Frontier Airlines
12 Oct LOT

Also check the deals for return flights from Chicago to Istanbul in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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