Cheapest one-way flights from Chicago to Istanbul in October from 220€

AirHint found the following cheapest one-way flights from Chicago (ORD) to Istanbul (IST) in October 2025 (see full year).

One-Way flights

06 Oct Frontier Airlines
03 Oct Frontier Airlines
01 Oct Spirit Airlines
02 Oct Spirit Airlines
08 Oct Delta
01 Oct Turkish Airlines direct
02 Oct Turkish Airlines direct
06 Oct Turkish Airlines direct
03 Oct Turkish Airlines direct

Also check the deals for return flights from Chicago to Istanbul in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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