Cheapest one-way flights from Chicago to Brussels in December from 290€

AirHint found the following cheapest one-way flights from Chicago (ORD) to Brussels (BRU) in December 2025 (see full year).

One-Way flights

12 Dec Frontier Airlines
04 Dec Spirit Airlines
11 Dec Spirit Airlines
10 Dec Icelandair
15 Dec Frontier Airlines
17 Dec Frontier Airlines
25 Dec Frontier Airlines
26 Dec Frontier Airlines
25 Dec United direct
17 Dec Brussels Airlines direct

Also check the deals for return flights from Chicago to Brussels in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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