AirHint found the following cheapest one-way flights from Porto (OPO) to Istanbul (IST) in December 2025 (see full year).

One-Way flights

01 Dec	easyJet
11 Dec	easyJet
31 Dec	Vueling Airlines
17 Dec	TAP
06 Dec	Vueling Airlines
27 Dec	Vueling Airlines
17 Dec	Turkish Airlines	direct
11 Dec	Turkish Airlines	direct
31 Dec	Turkish Airlines	direct
01 Dec	Turkish Airlines	direct

Also check the deals for return flights from Porto to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Porto to Istanbul in December from 96€

One-Way flights