Cheapest one-way flights from New York to Santiago in October from 221€

AirHint found the following cheapest one-way flights from New York (NYC) to Santiago (SCL) in October 2025 (see full year).

One-Way flights

01 Oct Frontier Airlines
31 Oct Spirit Airlines
11 Oct Frontier Airlines
10 Oct Avianca
15 Oct LATAM Airlines Group
30 Oct LATAM Airlines Group
07 Oct LATAM Airlines Group
29 Oct LATAM Airlines Group
02 Oct LATAM Airlines Group
27 Oct LATAM Airlines Group

Also check the deals for return flights from New York to Santiago in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago

Feel free to contact us with any feedback or request another flight research.