AirHint found the following cheapest one-way flights from Myrtle Beach (MYR) to Philadelphia (PHL) in October 2025 (see full year).

One-Way flights

02 Oct	Frontier Airlines	direct
09 Oct	Frontier Airlines	direct
12 Oct	Frontier Airlines	direct
16 Oct	Frontier Airlines	direct
19 Oct	Frontier Airlines	direct
23 Oct	Frontier Airlines	direct
26 Oct	Frontier Airlines	direct
04 Oct	Frontier Airlines	direct
08 Oct	Spirit Airlines
17 Oct	Spirit Airlines

Also check the deals for return flights from Myrtle Beach to Philadelphia in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Myrtle Beach to Philadelphia in October from 47€

One-Way flights