AirHint found the following cheapest one-way flights from Milano (MXP) to Brussels (BRU) in December 2025 (see full year).

One-Way flights

18 Dec	Vueling Airlines
07 Dec	Vueling Airlines
09 Dec	Wizz Air Malta
24 Dec	Vueling Airlines
20 Dec	Vueling Airlines
12 Dec	Vueling Airlines
21 Dec	Vueling Airlines
06 Dec	Vueling Airlines
23 Dec	Vueling Airlines
28 Dec	Ryanair

Also check the deals for return flights from Milano to Brussels in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Brussels

Cheap car rent in Brussels

Cheapest one-way flights from Milano to Brussels in December from 49€

One-Way flights