AirHint found the following cheapest one-way flights from Melbourne (MEL) to Karachi (KHI) in September 2025 (see full year).

One-Way flights

12 Sep	Batik Air
11 Sep	AirAsia X
29 Sep	Batik Air Malaysia
27 Sep	Batik Air Malaysia
28 Sep	Batik Air Malaysia
26 Sep	VietJet Air
24 Sep	VietJet Air
25 Sep	Batik Air Malaysia
22 Sep	Virgin Australia
23 Sep	Jetstar

Also check the deals for return flights from Melbourne to Karachi in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Melbourne to Karachi in September from 355€

One-Way flights