AirHint found the following cheapest one-way flights from Chicago (MDW) to Tampa (TPA) in November 2025 (see full year).

One-Way flights

02 Nov	Frontier Airlines	direct
03 Nov	Frontier Airlines	direct
09 Nov	Frontier Airlines	direct
14 Nov	Frontier Airlines	direct
10 Nov	Frontier Airlines	direct
07 Nov	Frontier Airlines
20 Nov	Frontier Airlines	direct
07 Nov	Frontier Airlines	direct
21 Nov	Delta
21 Nov	Southwest Airlines	direct

Also check the deals for return flights from Chicago to Tampa in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Chicago to Tampa in November from 38€

One-Way flights