Cheapest one-way flights from Chicago to St. Louis in October from 39€

AirHint found the following cheapest one-way flights from Chicago (MDW) to St. Louis (STL) in October 2025 (see full year).

One-Way flights

11 Oct Southwest Airlines direct
18 Oct Southwest Airlines direct

Also check the deals for return flights from Chicago to St. Louis in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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