Cheapest one-way flights from Madrid to Santiago in December from 25€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santiago (SCQ) in December 2025 (see full year).

One-Way flights

03 Dec Iberia direct
05 Dec Iberia direct
28 Dec Iberia direct
25 Dec Iberia direct
15 Dec Iberia direct
07 Dec Iberia direct
08 Dec Iberia direct
09 Dec Iberia direct
02 Dec Iberia direct
04 Dec Iberia direct

Also check the deals for return flights from Madrid to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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