Cheapest one-way flights from Madrid to Santiago in December from 488€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santiago (SCL) in December 2026 (see full year).

One-Way flights

07 Dec Avianca
04 Dec Avianca
07 Dec LATAM Airlines Group direct
04 Dec LATAM Airlines Group direct
22 Dec LATAM Airlines Group
16 Dec Iberia
23 Dec LATAM Airlines Group
20 Dec Iberia
21 Dec Ryanair
23 Dec Iberia direct

Also check the deals for return flights from Madrid to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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