Cheapest one-way flights from Madrid to Santiago in December from 471€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santiago (SCL) in December 2026 (see full year).

One-Way flights

04 Dec Avianca
04 Dec LATAM Airlines Group direct
01 Dec Avianca
01 Dec LATAM Airlines Group direct
18 Dec Ryanair
16 Dec Iberia direct
18 Dec Iberia direct
09 Dec Iberia direct
31 Dec Iberia direct
20 Dec Iberia direct

Also check the deals for return flights from Madrid to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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