Cheapest one-way flights from Madrid to Santiago in December from 486€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santiago (SCL) in December 2026 (see full year).

One-Way flights

24 Dec Transavia France
25 Dec Iberia
22 Dec Iberia Express
05 Dec Transavia France
23 Dec Air Europa
29 Dec LATAM Airlines Group direct
21 Dec LATAM Airlines Group direct
22 Dec LATAM Airlines Group direct
23 Dec LATAM Airlines Group direct
16 Dec Wizz Air Malta

Also check the deals for return flights from Madrid to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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