Cheapest one-way flights from Madrid to Santiago in December from 474€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santiago (SCL) in December 2026 (see full year).

One-Way flights

14 Dec Air Canada
01 Dec Air Europa
31 Dec Avianca
30 Dec Avianca
01 Dec LATAM Airlines Group direct
25 Dec LATAM Airlines Group direct
22 Dec LATAM Airlines Group direct
31 Dec LATAM Airlines Group direct
30 Dec LATAM Airlines Group direct
29 Dec Air Europa

Also check the deals for return flights from Madrid to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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