Cheapest one-way flights from Madrid to Santiago in January from 451€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santiago (SCL) in January 2026 (see full year).

One-Way flights

26 Jan Ryanair
24 Jan Ryanair
25 Jan Ryanair
29 Jan LATAM Airlines Group
17 Jan LATAM Airlines Group direct
23 Jan Wizz Air Malta
18 Jan LATAM Airlines Group direct
29 Jan LATAM Airlines Group direct
20 Jan LATAM Airlines Group
19 Jan LATAM Airlines Group

Also check the deals for return flights from Madrid to Santiago in January.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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