Cheapest one-way flights from Madrid to Prague in December from 46€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Prague (PRG) in December 2025 (see full year).

One-Way flights

14 Dec Ryanair direct
02 Dec Wizz Air Malta
13 Dec Ryanair direct
31 Dec Ryanair direct
17 Dec Wizz Air Malta
01 Dec Wizz Air Malta
09 Dec Wizz Air Malta
18 Dec Wizz Air Malta
03 Dec Wizz Air Malta
22 Dec Ryanair direct

Also check the deals for return flights from Madrid to Prague in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague

Feel free to contact us with any feedback or request another flight research.