Cheapest one-way flights from Madrid to Prague in December from 40€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Prague (PRG) in December 2025 (see full year).

One-Way flights

23 Dec Ryanair direct
28 Dec Ryanair direct
30 Dec Ryanair direct
31 Dec Ryanair direct
22 Dec Ryanair
27 Dec Ryanair direct
24 Dec Iberia
25 Dec Iberia
24 Dec Smart Wings direct
21 Dec Iberia Express

Also check the deals for return flights from Madrid to Prague in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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