AirHint found the following cheapest one-way flights from Madrid (MAD) to Lisbon (LIS) in December 2025 (see full year).

One-Way flights

16 Dec	TAP	direct
10 Dec	easyJet	direct
09 Dec	easyJet	direct
02 Dec	easyJet	direct
13 Dec	easyJet	direct
14 Dec	easyJet	direct
07 Dec	easyJet	direct
04 Dec	Air Europa	direct
15 Dec	Iberia	direct
06 Dec	Ryanair	direct

Also check the deals for return flights from Madrid to Lisbon in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Madrid to Lisbon in December from 25€

One-Way flights