AirHint found the following cheapest one-way flights from Madrid (MAD) to Istanbul (IST) in April 2026 (see full year).
One-Way flights
| 15 Apr | Wizz Air UK | ||
| 25 Apr | Wizz Air UK | ||
| 16 Apr | Wizz Air UK | ||
| 17 Apr | Wizz Air UK | ||
| 21 Apr | Wizz Air UK | ||
| 28 Apr | Wizz Air UK | ||
| 18 Apr | Wizz Air UK | ||
| 08 Apr | Ryanair | ||
| 24 Apr | Wizz Air UK | ||
| 20 Apr | Wizz Air UK |
Also check the deals for return flights from Madrid to Istanbul in April.
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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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