AirHint found the following cheapest one-way flights from Madrid (MAD) to Guayaquil (GYE) in November 2025 (see full year).
One-Way flights
| 17 Nov | Ryanair | ||
| 18 Nov | Iberojet | ||
| 23 Nov | TAP | ||
| 25 Nov | TAP | ||
| 19 Nov | TAP | ||
| 20 Nov | Iberia | ||
| 22 Nov | Ryanair | ||
| 21 Nov | Vueling Airlines | ||
| 15 Nov | Air Europa | ||
| 26 Nov | Royal Air Maroc |
Also check the deals for return flights from Madrid to Guayaquil in November.
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