Cheapest one-way flights from Madrid to Brussels in September from 38€

Best time to book flights for Madrid (MAD) to Brussels (BRU) flights at AirHint

AirHint found the following cheapest one-way flights from Madrid (MAD) to Brussels (BRU) in September 2025 (see full year).

One-Way flights

06 Sep Ryanair direct
25 Sep Ryanair direct
24 Sep Ryanair direct
05 Sep Ryanair direct
23 Sep Ryanair direct
27 Sep Ryanair direct
04 Sep Ryanair direct
26 Sep Ryanair direct
13 Sep Ryanair direct
12 Sep Ryanair direct

Also check the deals for return flights from Madrid to Brussels in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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