Cheapest one-way flights from Lyon to Brussels in December from 49€

AirHint found the following cheapest one-way flights from Lyon (LYS) to Brussels (BRU) in December 2025 (see full year).

One-Way flights

15 Dec Vueling Airlines
01 Dec Vueling Airlines
22 Dec Vueling Airlines
21 Dec Vueling Airlines
23 Dec KLM
05 Dec Vueling Airlines
15 Dec Brussels Airlines direct
23 Dec Brussels Airlines direct
22 Dec Brussels Airlines direct
30 Dec Vueling Airlines

Also check the deals for return flights from Lyon to Brussels in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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