AirHint found the following cheapest one-way flights from London (LON) to Lyon (LYS) in September 2025 (see full year).

One-Way flights

27 Sep	easyJet	direct
28 Sep	easyJet	direct
24 Sep	easyJet	direct
30 Sep	easyJet
29 Sep	easyJet	direct
21 Sep	easyJet	direct
20 Sep	easyJet	direct
30 Sep	easyJet	direct
23 Sep	Ryanair
25 Sep	easyJet	direct

Also check the deals for return flights from London to Lyon in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from London to Lyon in September from 25€

One-Way flights