AirHint found the following cheapest one-way flights from Lisbon (LIS) to Madrid (MAD) in November 2025 (see full year).

One-Way flights

27 Nov	TAP	direct
01 Nov	TAP	direct
22 Nov	Ryanair	direct
13 Nov	Ryanair	direct
20 Nov	Ryanair	direct
03 Nov	Ryanair	direct
08 Nov	Ryanair	direct
30 Nov	Ryanair	direct
21 Nov	TAP	direct
23 Nov	TAP	direct

Also check the deals for return flights from Lisbon to Madrid in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from Lisbon to Madrid in November from 22€

One-Way flights