AirHint found the following cheapest one-way flights from London (LGW) to Santiago (SCQ) in October 2025 (see full year).

One-Way flights

05 Oct	Vueling Airlines	direct
08 Oct	Vueling Airlines	direct
19 Oct	Vueling Airlines	direct
20 Oct	Vueling Airlines	direct
16 Oct	Vueling Airlines	direct
23 Oct	Vueling Airlines	direct
11 Oct	Vueling Airlines	direct
12 Oct	Vueling Airlines	direct
25 Oct	Vueling Airlines	direct
27 Oct	Vueling Airlines

Also check the deals for return flights from London to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest one-way flights from London to Santiago in October from 23€

One-Way flights