AirHint found the following cheapest one-way flights from New York (JFK) to Santiago (SCL) in October 2025 (see full year).

One-Way flights

06 Oct	Frontier Airlines
20 Oct	Avianca
09 Oct	Avianca
23 Oct	Avianca
10 Oct	Avianca
13 Oct	LATAM Airlines Group
16 Oct	Frontier Airlines
27 Oct	LATAM Airlines Group
30 Oct	LATAM Airlines Group
31 Oct	LATAM Airlines Group

Also check the deals for return flights from New York to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago

Cheapest one-way flights from New York to Santiago in October from 213€

One-Way flights