AirHint found the following cheapest one-way flights from Nis (INI) to Istanbul (IST) in December 2025 (see full year).
One-Way flights
| 06 Dec | Air Serbia | direct | |
| 20 Dec | Air Serbia | direct | |
| 23 Dec | Air Serbia | direct | |
| 27 Dec | Air Serbia | direct | |
| 05 Dec | Wizz Air Malta | ||
| 28 Dec | Air Serbia | ||
| 26 Dec | Ryanair |
Also check the deals for return flights from Nis to Istanbul in December.
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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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