Cheapest one-way flights from Houston to Panama City in December from 143€

AirHint found the following cheapest one-way flights from Houston (IAH) to Panama City (PTY) in December 2025 (see full year).

One-Way flights

31 Dec Spirit Airlines
14 Dec Spirit Airlines
15 Dec Spirit Airlines
16 Dec Spirit Airlines
06 Dec Frontier Airlines
17 Dec Spirit Airlines
23 Dec Spirit Airlines
22 Dec Spirit Airlines
05 Dec Frontier Airlines
18 Dec Spirit Airlines

Also check the deals for return flights from Houston to Panama City in December.

Powered by

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City

Feel free to contact us with any feedback or request another flight research.