AirHint found the following cheapest one-way flights from Houston (IAH) to Panama City (PTY) in December 2025 (see full year).
One-Way flights
| 30 Dec | Volaris | ||
| 28 Dec | Spirit Airlines | ||
| 22 Dec | Avianca | ||
| 21 Dec | Avianca | ||
| 24 Dec | United | direct | |
| 22 Dec | United | direct | |
| 21 Dec | United | direct | |
| 30 Dec | United | direct | |
| 28 Dec | United | direct |
Also check the deals for return flights from Houston to Panama City in December.
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