Cheapest one-way flights from Guayaquil to Santiago in December from 141€

AirHint found the following cheapest one-way flights from Guayaquil (GYE) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

28 Dec Avianca
08 Dec Avianca
09 Dec Avianca
10 Dec Avianca
08 Dec LATAM Airlines Group direct
10 Dec LATAM Airlines Group direct
09 Dec LATAM Airlines Group direct
06 Dec LATAM Airlines Group direct
16 Dec Copa
28 Dec LATAM Airlines Group direct

Also check the deals for return flights from Guayaquil to Santiago in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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