Cheapest one-way flights from Guayaquil to Santiago in December from 161€

AirHint found the following cheapest one-way flights from Guayaquil (GYE) to Santiago (SCL) in December 2025 (see full year).

One-Way flights

24 Dec LATAM Airlines Group direct
10 Dec LATAM Airlines Group
16 Dec LATAM Airlines Group direct
22 Dec LATAM Airlines Group
31 Dec LATAM Airlines Group
13 Dec LATAM Airlines Group
19 Dec LATAM Airlines Group
28 Dec LATAM Airlines Group
29 Dec LATAM Airlines Group
11 Dec LATAM Airlines Group

Also check the deals for return flights from Guayaquil to Santiago in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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