AirHint found the following cheapest one-way flights from Florence (FLR) to Brussels (BRU) in December 2025 (see full year).

One-Way flights

11 Dec	Vueling Airlines	direct
04 Dec	Vueling Airlines	direct
21 Dec	Vueling Airlines	direct
28 Dec	Vueling Airlines	direct
13 Dec	Vueling Airlines
19 Dec	Vueling Airlines
24 Dec	Vueling Airlines
22 Dec	Vueling Airlines
05 Dec	Vueling Airlines

Also check the deals for return flights from Florence to Brussels in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Brussels

Cheap car rent in Brussels

Cheapest one-way flights from Florence to Brussels in December from 38€

One-Way flights