AirHint found the following cheapest one-way flights from Medellin (EOH) to Santiago (SCL) in December 2025 (see full year).
One-Way flights
| 16 Dec | Avianca | ||
| 03 Dec | Avianca | ||
| 04 Dec | Avianca | ||
| 11 Dec | Avianca | ||
| 17 Dec | Avianca | ||
| 08 Dec | Avianca | ||
| 12 Dec | Avianca | ||
| 01 Dec | Avianca | ||
| 10 Dec | Clic Air | ||
| 05 Dec | Clic Air |
Also check the deals for return flights from Medellin to Santiago in December.
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