Cheapest one-way flights from Detroit to Rome in September from 182€

AirHint found the following cheapest one-way flights from Detroit (DTW) to Rome (FCO) in September 2025 (see full year).

One-Way flights

08 Sep Spirit Airlines
15 Sep Spirit Airlines
09 Sep Delta direct
15 Sep Air France direct
21 Sep Delta direct
29 Sep Air France direct
22 Sep Delta direct
08 Sep Air France direct
12 Sep Delta direct

Also check the deals for return flights from Detroit to Rome in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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