AirHint found the following cheapest one-way flights from Detroit (DTW) to Rome (FCO) in December 2025 (see full year).
One-Way flights
| 30 Dec | Spirit Airlines | ||
| 29 Dec | Icelandair | ||
| 31 Dec | Spirit Airlines | ||
| 28 Dec | Frontier Airlines | ||
| 28 Dec | Delta | direct | |
| 29 Dec | Delta | direct | |
| 31 Dec | Air France | direct | |
| 30 Dec | Air France | direct |
Also check the deals for return flights from Detroit to Rome in December.
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