Cheapest one-way flights from Des Moines to Jacksonville in October from 38€

AirHint found the following cheapest one-way flights from Des Moines (DSM) to Jacksonville (JAX) in October 2025 (see full year).

One-Way flights

09 Oct Allegiant Air direct

Also check the deals for return flights from Des Moines to Jacksonville in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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