AirHint found the following cheapest one-way flights from Denver (DEN) to Panama City (PTY) in December 2025 (see full year).
One-Way flights
| 20 Dec | Frontier Airlines | ||
| 01 Dec | Copa | direct | |
| 02 Dec | Copa | direct | |
| 03 Dec | Copa | direct | |
| 04 Dec | Copa | direct | |
| 07 Dec | Copa | direct | |
| 09 Dec | Copa | direct | |
| 11 Dec | Copa | direct | |
| 13 Dec | Copa | direct | |
| 16 Dec | Copa | direct |
Also check the deals for return flights from Denver to Panama City in December.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
Find us on social media