AirHint found the following cheapest one-way flights from Denver (DEN) to Sao Paulo (GRU) in December 2025 (see full year).
One-Way flights
| 30 Dec | Frontier Airlines | ||
| 20 Dec | Frontier Airlines | ||
| 23 Dec | Frontier Airlines | ||
| 29 Dec | Copa | ||
| 26 Dec | LATAM Airlines Group |
Also check the deals for return flights from Denver to Sao Paulo in December.
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