AirHint found the following cheapest return flights from Quito (UIO) to Rio Negro (MDE) in September 2025 (see full year).

Return flights

30 Sep - 11 Oct	Avianca
22 Sep - 23 Oct	Avianca
22 Sep - 27 Sep	Avianca	direct
20 Sep - 27 Sep	Avianca	direct
21 Sep - 22 Sep	Avianca	direct
20 Sep - 22 Sep	Avianca	direct
30 Sep - 02 Oct	Avianca
21 Sep - 22 Oct	Avianca	direct
26 Sep - 29 Sep	Avianca
22 Sep - 28 Sep	Avianca
16 Sep - 23 Sep	Avianca
21 Sep - 28 Sep	Avianca
17 Sep - 24 Sep	Avianca
17 Sep - 21 Sep	LATAM Airlines Group

Also check the deals for one-way flights from Quito to Rio Negro in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Rio Negro in September from 239€

Return flights