AirHint found the following cheapest return flights from Quito (UIO) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

23 Dec - 27 Dec	Copa
30 Dec - 17 Jan	LATAM Airlines Group
30 Dec - 17 Jan	Avianca	direct
21 Dec - 22 Dec	Avianca
21 Dec - 07 Jan	Avianca
20 Dec - 24 Dec	Avianca
28 Dec - 07 Jan	LATAM Airlines Group
24 Dec - 31 Dec	LATAM Airlines Group
28 Dec - 01 Jan	LATAM Airlines Group
26 Dec - 30 Dec	Copa
23 Dec - 25 Dec	LATAM Airlines Group
25 Dec - 01 Jan	LATAM Airlines Group
23 Dec - 01 Jan	LATAM Airlines Group
25 Dec - 06 Jan	Copa
22 Dec - 06 Jan	Avianca
20 Dec - 06 Jan	LATAM Airlines Group
23 Dec - 25 Dec	Avianca	direct
20 Dec - 23 Dec	Avianca	direct

Also check the deals for one-way flights from Quito to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Rio Negro in December from 249€

Return flights