AirHint found the following cheapest return flights from Quito (UIO) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

13 Dec - 16 Dec	Avianca
02 Dec - 03 Dec	LATAM Airlines Group
02 Dec - 06 Dec	LATAM Airlines Group
08 Dec - 12 Dec	Avianca
06 Dec - 11 Dec	Copa
01 Dec - 10 Dec	Copa
02 Dec - 09 Dec	Copa
02 Dec - 06 Dec	Avianca	direct
06 Dec - 20 Jan	Copa
02 Dec - 09 Dec	Avianca	direct
06 Dec - 20 Jan	Avianca	direct
27 Dec - 01 Jan	Avianca	direct
27 Dec - 08 Jan	Avianca	direct
06 Dec - 15 Jan	Avianca	direct
29 Dec - 01 Jan	Avianca
09 Dec - 13 Dec	LATAM Airlines Group
03 Dec - 17 Jan	Avianca
31 Dec - 07 Jan	Avianca
05 Dec - 14 Jan	Avianca
04 Dec - 14 Jan	Avianca

Also check the deals for one-way flights from Quito to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Rio Negro in December from 241€

Return flights