AirHint found the following cheapest return flights from Split (SPU) to Istanbul (IST) in September 2025 (see full year).

Return flights

16 Sep - 21 Sep	Vueling Airlines
02 Sep - 05 Sep	Croatia Airlines	direct
20 Sep - 29 Sep	Croatia Airlines	direct
20 Sep - 28 Sep	Croatia Airlines	direct
14 Sep - 20 Sep	Croatia Airlines	direct
14 Sep - 21 Sep	Croatia Airlines	direct
16 Sep - 21 Sep	Croatia Airlines	direct
18 Sep - 25 Sep	Wizz Air UK
06 Sep - 07 Sep	Croatia Airlines	direct
04 Sep - 12 Sep	Croatia Airlines	direct
20 Sep - 04 Oct	Croatia Airlines	direct

Also check the deals for one-way flights from Split to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Split to Istanbul in September from 142€

Return flights