AirHint found the following cheapest return flights from Southampton (SOU) to Milano (MXP) in September 2025 (see full year).

Return flights

28 Sep - 05 Oct	Aer Lingus
01 Sep - 05 Sep	easyJet
21 Sep - 24 Sep	Aer Lingus
01 Sep - 06 Sep	easyJet
13 Sep - 30 Sep	Aer Lingus
11 Sep - 17 Sep	easyJet
10 Sep - 12 Sep	Aer Lingus
08 Sep - 11 Sep	Aer Lingus

Also check the deals for one-way flights from Southampton to Milano in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Southampton to Milano in September from 178€

Return flights