AirHint found the following cheapest return flights from San Francisco (SFO) to Guangzhou (CAN) in September 2025 (see full year).

Return flights

22 Sep - 19 Oct	Cathay Pacific
18 Sep - 06 Oct	Cathay Pacific
23 Sep - 09 Oct	Cathay Pacific
24 Sep - 15 Oct	Cathay Pacific
17 Sep - 21 Oct	Cathay Pacific
08 Sep - 15 Sep	Cathay Pacific
09 Sep - 16 Sep	Cathay Pacific
05 Sep - 18 Sep	China Southern
14 Sep - 25 Sep	Cathay Pacific
10 Sep - 25 Oct	Cathay Pacific
28 Sep - 20 Oct	Cathay Pacific
07 Sep - 20 Sep	Cathay Pacific
07 Sep - 20 Sep	China Southern	direct
17 Sep - 21 Oct	China Southern	direct
01 Sep - 14 Sep	Alaska Airlines

Also check the deals for one-way flights from San Francisco to Guangzhou in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Guangzhou in September from 633€

Return flights