AirHint found the following cheapest return flights from Santo Domingo (SDQ) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

05 Dec - 12 Dec	Arajet	direct
28 Dec - 17 Jan	Arajet
09 Dec - 16 Dec	Copa
09 Dec - 12 Dec	Copa
09 Dec - 13 Dec	Copa
27 Dec - 15 Jan	Wingo	direct
12 Dec - 19 Dec	Arajet	direct
04 Dec - 11 Dec	Wingo	direct
12 Dec - 15 Dec	Arajet
05 Dec - 08 Dec	Arajet
14 Dec - 14 Jan	Arajet	direct
12 Dec - 16 Dec	Copa
13 Dec - 16 Dec	Copa
18 Dec - 23 Jan	Frontier Airlines
30 Dec - 01 Jan	Wingo	direct
31 Dec - 08 Jan	Avianca
18 Dec - 23 Jan	Arajet	direct
27 Dec - 10 Jan	Wingo	direct
31 Dec - 08 Jan	Arajet	direct
28 Dec - 06 Jan	Arajet

Also check the deals for one-way flights from Santo Domingo to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santo Domingo to Rio Negro in December from 223€

Return flights