AirHint found the following cheapest return flights from Santiago (SCQ) to Istanbul (IST) in September 2025 (see full year).

Return flights

10 Sep - 14 Sep	Vueling Airlines
25 Sep - 02 Oct	Ryanair
20 Sep - 26 Sep	Ryanair
29 Sep - 06 Oct	Ryanair
08 Sep - 14 Sep	Vueling Airlines
15 Sep - 20 Sep	Ryanair
18 Sep - 22 Sep	Vueling Airlines
06 Sep - 13 Sep	Ryanair
14 Sep - 21 Sep	Vueling Airlines
07 Sep - 13 Sep	Vueling Airlines
01 Sep - 08 Sep	Vueling Airlines
29 Sep - 14 Oct	Vueling Airlines
29 Sep - 15 Oct	Vueling Airlines
29 Sep - 11 Oct	Vueling Airlines
03 Sep - 22 Sep	Vueling Airlines
29 Sep - 02 Oct	Vueling Airlines
15 Sep - 02 Oct	Vueling Airlines
14 Sep - 02 Oct	Vueling Airlines

Also check the deals for one-way flights from Santiago to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Istanbul in September from 181€

Return flights