AirHint found the following cheapest return flights from Santiago (SCQ) to Brussels (BRU) in April 2026 (see full year).

Return flights

08 Apr - 11 Apr	Vueling Airlines
08 Apr - 28 Apr	Vueling Airlines
21 Apr - 09 May	Vueling Airlines
21 Apr - 28 Apr	Vueling Airlines
07 Apr - 11 Apr	Iberia
14 Apr - 28 Apr	Ryanair	direct
14 Apr - 28 Apr	Vueling Airlines
25 Apr - 16 May	Ryanair	direct
25 Apr - 09 May	Ryanair	direct
25 Apr - 28 Apr	Ryanair	direct
16 Apr - 28 Apr	Vueling Airlines
08 Apr - 13 Apr	Vueling Airlines
08 Apr - 12 Apr	Iberia
21 Apr - 09 May	Ryanair	direct

Also check the deals for one-way flights from Santiago to Brussels in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Brussels in April from 141€

Return flights