AirHint found the following cheapest return flights from Santiago (SCQ) to Brussels (BRU) in October 2025 (see full year).

Return flights

20 Oct - 23 Oct	Ryanair	direct
13 Oct - 23 Oct	Ryanair	direct
13 Oct - 16 Oct	Ryanair	direct
16 Oct - 23 Oct	Ryanair	direct
13 Oct - 20 Oct	Ryanair	direct
16 Oct - 20 Oct	Ryanair	direct
20 Oct - 31 Oct	Ryanair
09 Oct - 23 Oct	Ryanair	direct
20 Oct - 28 Oct	Ryanair
09 Oct - 16 Oct	Ryanair	direct
20 Oct - 01 Nov	Ryanair
20 Oct - 05 Nov	Ryanair
16 Oct - 05 Nov	Ryanair
13 Oct - 01 Nov	Ryanair
30 Oct - 05 Nov	Ryanair
16 Oct - 01 Nov	Ryanair
17 Oct - 05 Nov	Vueling Airlines
24 Oct - 05 Nov	Vueling Airlines
18 Oct - 05 Nov	Vueling Airlines
23 Oct - 05 Nov	Vueling Airlines

Also check the deals for one-way flights from Santiago to Brussels in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Brussels in October from 70€

Return flights