AirHint found the following cheapest return flights from Santiago (SCL) to Quito (UIO) in December 2025 (see full year).

Return flights

31 Dec - 23 Jan	Avianca
17 Dec - 26 Dec	JetSmart
17 Dec - 31 Dec	JetSmart
17 Dec - 28 Dec	JetSmart
17 Dec - 24 Dec	JetSmart
17 Dec - 21 Dec	JetSmart
31 Dec - 11 Jan	JetSmart
17 Dec - 02 Jan	JetSmart
15 Dec - 31 Dec	LATAM Airlines Group
31 Dec - 09 Jan	JetSmart
12 Dec - 09 Jan	Avianca
08 Dec - 13 Dec	LATAM Airlines Group
16 Dec - 18 Dec	LATAM Airlines Group
15 Dec - 21 Dec	LATAM Airlines Group
17 Dec - 04 Jan	JetSmart
31 Dec - 02 Jan	JetSmart
15 Dec - 15 Jan	LATAM Airlines Group
31 Dec - 07 Jan	JetSmart
07 Dec - 26 Dec	JetSmart
31 Dec - 18 Jan	JetSmart

Also check the deals for one-way flights from Santiago to Quito in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Quito in December from 359€

Return flights