AirHint found the following cheapest return flights from Santiago (SCL) to Quito (UIO) in October 2025 (see full year).

Return flights

01 Oct - 08 Oct	JetSmart
01 Oct - 03 Oct	JetSmart
01 Oct - 05 Oct	JetSmart
01 Oct - 12 Oct	JetSmart
03 Oct - 08 Oct	JetSmart
01 Oct - 15 Oct	JetSmart
05 Oct - 08 Oct	JetSmart
03 Oct - 05 Oct	JetSmart
03 Oct - 12 Oct	JetSmart
29 Oct - 07 Nov	JetSmart
05 Oct - 12 Oct	JetSmart
29 Oct - 09 Nov	JetSmart
22 Oct - 07 Nov	JetSmart
29 Oct - 12 Nov	JetSmart
22 Oct - 09 Nov	JetSmart
31 Oct - 07 Nov	JetSmart
31 Oct - 09 Nov	JetSmart
31 Oct - 12 Nov	JetSmart

Also check the deals for one-way flights from Santiago to Quito in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Quito in October from 259€

Return flights